Keywords
neuroinflammation
cognitive decline
biomarkers
dementia
chronic disease
mental health
health policy
evidence-based medicine
patient outcomes
precision medicine
cardiovascular disease
public health
diagnosis
cognitive decline
biomarkers
dementia
chronic disease
mental health
health policy
evidence-based medicine
patient outcomes
precision medicine
cardiovascular disease
public health
diagnosis
Abstract
Chronic neuroinflammation is implicated in cognitive ageing. We tracked plasma inflammatory markers and cognition in 1,800 older adults over eight years.
Elevated baseline neuroinflammatory markers predicted accelerated cognitive decline independent of amyloid status, highlighting inflammation as a modifiable target.
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